


A Conservative, Non-Opioid Pain Relief Option
As the demand for opioid-free alternatives grows, solutions like Trubrexa® are stepping up to deliver meaningful results for patients & providers.

30-Day Supply
NDC 83295-4000-1
4-Day Supply
NDC 83295-4000-4
Trubrexa® Transdermal Patch is indicated in adults over the age of 12 years old for the treatment of acute and chronic pain in muscles and joints associated with muscle soreness, strains, sprains, arthritis, simple backache, muscle stiffness, and more.
Trubrexa® Transdermal Patch is contraindicated in patients with a known history of sensitivity to local anesthetics of the amide type, or to any other component of the product.



Trubrexa Advantage
®
Discover the advantages of our unique patch design:
Transdermal systems are able to penetrate deeper than topical formulations. Unlock the benefits of transdermal technology for more efficient medication delivery.
4
Flexible, Breathable Fabric
Comfortable application for long-wear
3
Extended Time Release
Constant and controlled medication administration
2
Patented Water-Based Hydrogel Adhesive
Durable design for uncompromised adhesion
1
Matrix-Style Transdermal Delivery
Deeper penetration than topical formulations


Epidermis
Dermis
Hypodermis & Muscle

Improving Outcomes
See what pain management professionals are saying about Trubrexa®
"As a pain management specialist, I’ve witnessed firsthand the transformative impact Trubrexa® Transdermal Patches have had on my patients’ treatment plans. These patches have become a valuable tool in reducing reliance on oral narcotics, offering targeted relief without the side effects often associated with traditional pain medications.
Since incorporating Trubrexa® into my practice, I’ve seen a measurable decrease in the volume of opioid prescriptions. Patients consistently report meaningful pain relief and improved function, and many now arrive at follow-up appointments specifically requesting more, a testament to both its efficacy and tolerability.
Trubrexa® has become a trusted part of my multimodal pain management approach, and I’m optimistic about its continued evolution in meeting the diverse needs of our patient population."
- R. Gupta, PM&R Physician

"I’ve spent years helping patients navigate pain as an orthopedic surgeon, yet nothing quite prepares you for when it’s your own. After developing a pinched nerve in my neck, I found myself in the same frustrating cycle I often hear about from my patients: sleepless nights, limited mobility, and a growing list of treatments that offered little relief. I tried everything; but the pain persisted.
It wasn’t until I applied Trubrexa® that I finally experienced meaningful relief. Within hours, the sharp, radiating discomfort began to ease. For the first time in weeks, I was able to rest. And more importantly, I felt like I was finally on the mend.
That experience reshaped how I approach pain management in my own practice. Trubrexa® is one I now recommend with firsthand confidence. My patients appreciate its targeted delivery and non-narcotic formulation, and I’ve seen it reduce the need for oral pain medications across the board."
- A. Patel, DO

